Methyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate
3-Methoxycarbonylphenylboronic acid pinacol ester
CAS: 480425-35-2
Molecular Formula: C14H19BO4
Methyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate - Names and Identifiers
Methyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate - Physico-chemical Properties
| Molecular Formula | C14H19BO4 |
| Molar Mass | 262.11 |
| Density | 1.08±0.1 g/cm3(Predicted) |
| Melting Point | 91-95 °C (lit.) |
| Boling Point | 364.3±25.0 °C(Predicted) |
| Flash Point | 174.1°C |
| Water Solubility | Insoluble |
| Vapor Presure | 1.7E-05mmHg at 25°C |
| Appearance | powder to crystal |
| Color | White to Almost white |
| Storage Condition | Inert atmosphere,2-8°C |
| Refractive Index | 1.498 |
| MDL | MFCD03789258 |
Methyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| HS Code | 29310099 |
Methyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate - Introduction
Acid pinacol ester is an organic compound with the chemical formula C14H19BO4.
The compound has the following properties:
-Appearance: Colorless to light yellow solid
-Melting point: about 70-75°C
-Molecular weight: 246.11g/mol
-Solubility: Soluble in organic solvents such as dimethyl sulfoxide and chloroform
acid pinacol ester is mainly used in organic synthesis and is often used as a synthetic reagent for benzyl ketone compounds. It is a carboxylic acid derivative of carbonyl compounds, which can be used to synthesize drugs, pesticides, dyes and functional compounds.
Regarding the preparation method, a common synthesis method is to use the reaction of benzyl ketone and phenylboronic acid to generate the corresponding alcohol ester. The specific steps include the reaction of benzyl ketone and phenylboronic acid under the catalysis of a base to generate an acid, followed by an esterification reaction, and the final product is obtained by adding pinacol.
Regarding safety information, acid pinacol ester is a relatively safe compound under normal use conditions. However, it is still necessary to follow laboratory safety practices, such as wearing appropriate protective equipment (such as gloves, glasses, and lab clothes) to avoid contact with skin, eyes, and mouth. Avoid inhalation of dust or fumes during handling and ensure that the operating area is well ventilated. In case of accidental contact or inhalation, rinse immediately with plenty of water and seek medical help. In addition, the compound should be stored in a dry, dark place, away from fire and flammable substances. More detailed safety information can be found in the Safety Data Sheet (SDS) of the substance or in the relevant chemical literature.
The compound has the following properties:
-Appearance: Colorless to light yellow solid
-Melting point: about 70-75°C
-Molecular weight: 246.11g/mol
-Solubility: Soluble in organic solvents such as dimethyl sulfoxide and chloroform
acid pinacol ester is mainly used in organic synthesis and is often used as a synthetic reagent for benzyl ketone compounds. It is a carboxylic acid derivative of carbonyl compounds, which can be used to synthesize drugs, pesticides, dyes and functional compounds.
Regarding the preparation method, a common synthesis method is to use the reaction of benzyl ketone and phenylboronic acid to generate the corresponding alcohol ester. The specific steps include the reaction of benzyl ketone and phenylboronic acid under the catalysis of a base to generate an acid, followed by an esterification reaction, and the final product is obtained by adding pinacol.
Regarding safety information, acid pinacol ester is a relatively safe compound under normal use conditions. However, it is still necessary to follow laboratory safety practices, such as wearing appropriate protective equipment (such as gloves, glasses, and lab clothes) to avoid contact with skin, eyes, and mouth. Avoid inhalation of dust or fumes during handling and ensure that the operating area is well ventilated. In case of accidental contact or inhalation, rinse immediately with plenty of water and seek medical help. In addition, the compound should be stored in a dry, dark place, away from fire and flammable substances. More detailed safety information can be found in the Safety Data Sheet (SDS) of the substance or in the relevant chemical literature.
Last Update：2024-04-09 21:49:45
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Product Name: Methyl 3-(4,4,5,5-TETRAMethyl-1,3,2- Dioxaborolan-2-YL)Benzoate Visit Supplier Webpage Request for quotationCAS: 480425-35-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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